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Scientific American is aspect of Springer Nature, which owns or has commercial relations with thousands of scientific publications (quite a few of them can be found at /us). Scientific American maintains a strict policy of editorial independence in reporting developments in science to our readers. Continuous use of such drugs robs them of their power to induce euphoria. Addictive substances maintain the brain so awash in dopamine that it eventually adapts by making less of the molecule and becoming less responsive to its effects. As a consequence, addicts develop up a tolerance to a drug, needing bigger and bigger amounts...